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September 21, 202611 min readThree new papers from Amazon Bio Discovery address bottlenecks in AI-driven antibody engineering, from benchmarking binding predictors to experimentally validating de novo design.
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August 21, 20269 min read
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July 30, 20268 min read
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Featured news
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COLM 2026 Workshop on Lifelong Agents2026Multi-agent architectures today are hand-designed, generated one-shot, or evolved through unconstrained code search—none of which treats the number of agents as a searchable parameter, and none of which can discover that a single agent is optimal. We argue agent count and coordination topology should be optimized with the same discipline applied to neural architectures: bounded edits, held-out validation
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COLM 2026 Workshop on Efficient Reasoning2026The recent advancements in Vision Language Models (VLMs) have demonstrated progress toward true intelligence requiring robust reasoning capabilities. Beyond pattern recognition, linguistic reasoning must integrate with visual comprehension, particularly for Chart Question Answering (CQA) tasks involving complex data visualizations. Current VLMs face significant limitations in CQA, including imprecise numerical
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COLM 2026 Workshop on Agent Behavior2026Coordination interventions for multi-agent LLM systems are regime-dependent: identical guidance yields opposite effects at different decoding temperatures, improving accuracy in the deterministic regime but degrading it in the stochastic regime. The reversal traces to over-regularization: exploration-promoting interventions add explicit entropy to policies already receiving implicit entropy from stochastic
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2026Bee provides a personal AI assistant that uses frontier AI models over user-controlled real-world context. Privacy is a core system requirement: the architecture is designed to prevent Bee and other Amazon operators, non-attested internal services, and supporting infrastructure from accessing plaintext user data outside the user’s cryptographically authorized processing path. The Bee Private Compute architecture
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EMNLP 20262026Production tool calling for agentic systems must satisfy four operational requirements: lower per-invocation cost, low latency, adaptability to evolving tool catalogs, and the ability to catch errors before execution. The ReAct paradigm keeps the large language model (LLM) in the loop, but at production scale, reprocessing intermediate results inflates cost and latency and degrades answer quality. Programmatic
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