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A graphic shows a simulation of what a VR guided experience might look like, it features colored circles, a humanoid face, and other features
TRIPP is an Alexa Fund portfolio company that is exploring how virtual reality can be combined with meditation. The company's CEO and co-founder Nanea Reeves noted that the VR experiences "are deliberately psychedelic. You find yourself inside an atom or floating in space."
TRIPP

TRIPP explores the potential of virtual reality–powered meditation

Alexa Fund portfolio company’s science-led program could change how we approach mental wellness — and how we use VR.

By Staff writer
October 7, 2022
5 min read
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(Editor’s note: This article is the latest installment in a series by Amazon Science delving into the science behind products and services of companies in which Amazon has invested. The Alexa Fund participated in TRIPP’s $11.2M Series A extension funding round in June 2022.)

With meditation soaring in popularity and the virtual reality (VR) industry booming, Alexa Fund portfolio company TRIPP is at the confluence of two powerful trends: mental well-being and VR. TRIPP is a digital wellness program that uses VR headsets to immerse users in breathing meditation experiences.

The idea to meld meditation and VR first occurred to TRIPP CEO and co-founder Nanea Reeves in 2017 when she, a lifelong practitioner of meditation with a 15-year career in the gaming industry, was experimenting with the medium by building a solitaire game in VR.

This graphic shows a potential visualization from the VR app TRIPP, it includes a planet floating in space against a background featuring stars and bright colors
TRIPP CEO Nanea Reeves said she was inspired by the work of Giuseppe Riva, a neuropsychologist. “We wondered if we could create environments that make you go, ‘Oh, wow!’ and give you a lift,” Reeves explains.
TRIPP

“The way I felt exploring VR was even more interesting to me than the actual development,” Reeves says. Her interest developed into a deep curiosity about the psychological effects of VR, and she began searching the scientific literature.

In addition to studying VR in medical and mental health use cases, she discovered work by Giuseppe Riva, a neuropsychologist whose research has shown that VR can elicit emotions such as awe and, in turn, influence people’s well-being, agency, and perceptions of themselves.

“Inspired by Giuseppe’s research, we wondered if we could create environments that make you go, ‘Oh, wow!’ and give you a lift,” Reeves explains. That became her impetus to found TRIPP in 2017, pursuing the hypothesis that, by stimulating experiences through VR, people may gain some agency over their emotions.

Riva’s work identified several aspects of VR that made it particularly effective for evoking awe, including its immersive nature and the complexity and scale of virtual environments.

“We started leaning into that, and we started to play with scale in our designs,” says Reeves.

In 2019, TRIPP launched its award-winning wellness application, TRIPP, in VR. The application offers immersive mindfulness experiences and, to date, has delivered nearly 6 million wellness sessions. TRIPP continues to work closely with neuroscience and psychiatry advisors through PsyAssist to design and evaluate their experiences and with a host of researchers who are studying its potential uses.

A recent clinical trial suggested that TRIPP might positively influence well-being and mood in cancer patients, and ongoing projects are assessing whether TRIPP can help people in recovery from substance use disorders or anxiety and pain control, among other initiatives.

“With some of the early data coming in, it seems very promising that tools like TRIPP might have a positive impact,” Reeves says, “but we are still only at the beginning of what may be possible with VR.”

Amazon Science spoke with Reeves about the motivation for TRIPP, its roots in science, and the implications for what it can achieve with VR.

  1. Q. 

    Why take meditation virtual?
    A. 

    It’s actually a super native case for VR, because the immersive quality allows you to unplug. You can’t look at your phone by nature of the immersion. I was blown away by how I felt moving in and out of VR — the feeling of respite.

    A lot of the early VR experiences simulated environments that made you terrified, like walking a plank or standing at the edge of a cliff. And it occurred to me: if we could scare people so easily, could we trigger other emotional changes that are beneficial?

    Our approach is to use immersion to drive a deeper connection to self-contemplative thoughts. You’re immersed in this psychologically safe container that is designed to capture your awareness, to allow you to be present and connect to self. With VR, it’s not just an audio file guiding you toward connecting with your breath. We can show you your breath, like star crystals coming in and out of your mouth.

    Some of the early offerings thought VR was really only for gaming. When we first got TRIPP on Oculus, they didn’t know where to put us because they didn’t have a relaxation genre then. We were pretty buried in the store. But we started to get a little bit of traction, and we soon had surprisingly regular usage over time. VR has this problem where you go in, you go, “Wow, that was amazing!” and then it's in your closet. You never pick it up again. When we were designing the product, we knew we had to build for repeat usage. So, we built it procedurally, and now we can update it from the server and add new content regularly.

  2. Q. 

    How is science leading the design and development of TRIPP?
    A. 

    I started by looking at the research investigating VR’s effect on the brain, largely by neuroscientists and behavioral therapists exploring mental health and medical use cases for VR. Most of them focused on simulation, like simulated exposure therapy. But I wondered if, instead of simulating something, could we stimulate responses? I took that question to the researchers working on VR and its effects on mental well-being. We started digging into the research and then, based on the research data, designed VR experiences intended to trigger states of wonder and awe. We tried them out on people and captured some physiological data like heart rate and EEG to see if the experiences were directionally achieving the effect we wanted.

    We stay very grounded in research-driven design choices. We’re a bit edgy. Rather than mimicking natural environments, the experiences are deliberately psychedelic. You find yourself inside an atom or floating in space. First, we tried things like a waterfall or a beach, but when we tested them, they didn’t feel good. I found some research describing how sensory dissonance in synthetic natural environments can create a stress response. Your brain goes, “Well, it looks like a beach, but I don’t smell the ocean. So what’s wrong with this environment?” We realized we had to create environments for which you have no mental model. So we said, “OK, let’s put you in a cosmic flotation tank, whatever that means, because no one knows what space smells like.”

    We’re also starting an enterprise program to support employee wellness and team-building with a hybrid workforce, but also with a focus on using the metaverse for driving ideation and innovation. Can we use these otherworldly environments to spark creativity?
    Nanea Reeves

    After we launched, we started collecting data on mood and emotional state in the live user sessions via self-reported surveys that are based on what they use in mental health research. We bookended our sessions with users, basically asking “How do you feel?” before and after each session. We did things like randomizing the order of the response selections to control against position bias. Now, we have data collected from close to 6 million sessions that we can slice and dice by the time of day and, for a percentage of our audience who opted in, age, gender, and location. It’s become a meaningful body of data that we can share with researchers once it has been de-identified. We also work with researchers who want to study TRIPP and its potential applications. It’s been fascinating to work with that community.

    One example is this group in Germany working with cancer patients undergoing surgery, looking at the effects of TRIPP sessions on their quality of life, well-being, and mood. This study was published in Nature’s Scientific Reports. Participation was good, and patients who used TRIPP had lower heart rates and breathing rates after their sessions. They had improved scores on their mood and emotion surveys after the sessions too. What the study shows us is that VR-based relaxation is a viable option and may be beneficial for cancer patients undergoing surgery. Of course, we don’t make any therapeutic claims until we have a tremendous amount of evidence to support those claims.

    You can find other published data and scientific reports examining TRIPP’s effects on adolescents and its use in palliative care. And we’re working with researchers who are looking at whether TRIPP could help people experiencing addiction and rehab, chemotherapy, severe mental illness, anxiety, and pain. Researchers are also using TRIPP to ease anxiety and help people prepare for ketamine-assisted therapy, so they get the most out of their treatment. I feel very motivated to see how we can help and participate in these research initiatives.

  3. Q. 

    How might TRIPP change how we use VR, beyond its medical applications?
    A. 

    Earlier this year, we acquired EvolVR, which holds live group meditations. Several hundred avatars attend the most popular conversations. People really open up. Skip Rizzo, PhD, a renowned researcher in the field and an advisor to TRIPP, did a pilot study and found that people suffering from PTSD were more open and honest with an avatar. We want to further investigate this as there’s something about the “digital veil” of VR where you don’t feel the judgment of being seen by other people. I think this is a wonderful use case for the metaverse.

    We’re also starting an enterprise program to support employee wellness and team-building with a hybrid workforce, but also with a focus on using the metaverse for driving ideation and innovation. Can we use these otherworldly environments to spark creativity?

    It’s also fascinating to think about the gig economy that could emerge from the metaverse — similar to what first emerged from mobile computing. For example, I met a woman at one of our live group meditation events in the metaverse who’s earning a living as one of the top world-builders in Altspace VR. She’s a mother of five who has never worked in tech before. She’s now a programmer, building these virtual worlds.

    We’re only beginning to explore the potential of VR. It’s like the early days of mobile. Initially, no one thought we’d want to play games or even text message on our cell phones. Now, for the past decade, we have been walking around with our heads down staring at these phone screens nonstop. What kind of innovation will happen in a future when XR glasses are ubiquitous and allow us to experience the world around us in an entirely new and adaptive way?

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Senior Applied Scientist, Center for Quantum Computing: Device Team
US, CA, Pasadena
As a Senior Quantum Applied Scientist on our Device team, you will be a technical authority and driving force in the design and measurements of novel superconducting qubits. You will lead detailed simulation and measurement efforts to explain experimental results, inform new qubit designs, and optimize device performance, working collaboratively with our design, fabrication, processor, and exploratory research teams. This is a role with significant room for innovation: you will play a key role in finding paths towards more performant devices. We are looking for a seasoned researcher with deep expertise in superconducting circuit physics plus a proven track record of bridging design, simulation, and measurement. Success in this role requires both technical depth and a genuine passion for applied, collaborative work. The ideal candidate will excel at communication across disciplines — translating detailed analyses into actionable guidance for engineering teams — and will bring the experience and judgment to identify innovations that will have the greatest impact. Key job responsibilities • Develop simulations to predict device performance, then design and measure devices that leverage the understood scalings. • Reduce the gap between simulated predictions and measurements by building more accurate models. • Communicate scientific findings across the CQC, and, when appropriate, share results externally via conference presentations and publications in scientific journals • Identify and evaluate emerging research developments that could impact design decisions About the team The Amazon Center for Quantum Computing (CQC) is a multi-disciplinary team of scientists, engineers, and technicians, on a mission to develop a fault-tolerant quantum computer.
Sr. Data Scientist, Amazon Pay Data Products
IN, KA, Bengaluru
Amazon Pay strives to be Earth’s most customer-centric payments service. Our mission is to serve customers and merchant partners with the most trusted, friction-less and rewarding payment solutions for their needs on and off Amazon. We are seeking an exceptional Data Scientist III to drive innovation in machine learning and artificial intelligence solutions while leading high-impact initiatives across the organization. Key job responsibilities Technical Excellence Lead end-to-end machine learning projects using PyTorch, AWS SageMaker, and other leading ML frameworks Design and implement complex statistical models and deep learning solutions Develop and optimize MLOps pipelines for model training, evaluation, and deployment Experience with modern LLM frameworks and Generative AI applications Expertise in Python, R, and related data science libraries MLOps & Development Build automated ML pipelines using AWS services (CodePipeline, Lambda, Step Functions) Implement CI/CD practices for ML model deployment and monitoring Create containerized solutions using Docker for scalable model deployment Experience with model optimization and hyperparameter tuning using tools like Optuna Integrate ML solutions with monitoring tools like MLflow Business Impact & Leadership Partner with stakeholders to translate business problems into technical solutions Design and develop business intelligence applications for real-time insights Lead technical initiatives and mentor junior data scientists Drive cross-functional collaboration to deliver innovative solutions Communicate complex technical concepts to non-technical audiences About the team The Amazon Pay Data Products team is a central unit that builds and maintains data products supporting Amazon Pay's growth across multiple markets. We operate at scale, processing 150M+ monthly transactions and managing 12 PB of data infrastructure. Our team consists of Business Intelligence Engineers, Data Engineers, and Product Managers who develop and maintain standardized reporting, data marts, and self-service analytics tools. Our expanded capabilities cover data science and Gen AI wherein we have built our first suite of multi-agent systems.
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