A graphic shows a simulation of what a VR guided experience might look like, it features colored circles, a humanoid face, and other features
TRIPP is an Alexa Fund portfolio company that is exploring how virtual reality can be combined with meditation. The company's CEO and co-founder Nanea Reeves noted that the VR experiences "are deliberately psychedelic. You find yourself inside an atom or floating in space."
TRIPP

TRIPP explores the potential of virtual reality–powered meditation

Alexa Fund portfolio company’s science-led program could change how we approach mental wellness — and how we use VR.

(Editor’s note: This article is the latest installment in a series by Amazon Science delving into the science behind products and services of companies in which Amazon has invested. The Alexa Fund participated in TRIPP’s $11.2M Series A extension funding round in June 2022.)

With meditation soaring in popularity and the virtual reality (VR) industry booming, Alexa Fund portfolio company TRIPP is at the confluence of two powerful trends: mental well-being and VR. TRIPP is a digital wellness program that uses VR headsets to immerse users in breathing meditation experiences.

The idea to meld meditation and VR first occurred to TRIPP CEO and co-founder Nanea Reeves in 2017 when she, a lifelong practitioner of meditation with a 15-year career in the gaming industry, was experimenting with the medium by building a solitaire game in VR.

This graphic shows a potential visualization from the VR app TRIPP, it includes a planet floating in space against a background featuring stars and bright colors
TRIPP CEO Nanea Reeves said she was inspired by the work of Giuseppe Riva, a neuropsychologist. “We wondered if we could create environments that make you go, ‘Oh, wow!’ and give you a lift,” Reeves explains.
TRIPP

“The way I felt exploring VR was even more interesting to me than the actual development,” Reeves says. Her interest developed into a deep curiosity about the psychological effects of VR, and she began searching the scientific literature.

In addition to studying VR in medical and mental health use cases, she discovered work by Giuseppe Riva, a neuropsychologist whose research has shown that VR can elicit emotions such as awe and, in turn, influence people’s well-being, agency, and perceptions of themselves.

“Inspired by Giuseppe’s research, we wondered if we could create environments that make you go, ‘Oh, wow!’ and give you a lift,” Reeves explains. That became her impetus to found TRIPP in 2017, pursuing the hypothesis that, by stimulating experiences through VR, people may gain some agency over their emotions.

Riva’s work identified several aspects of VR that made it particularly effective for evoking awe, including its immersive nature and the complexity and scale of virtual environments.

“We started leaning into that, and we started to play with scale in our designs,” says Reeves.

In 2019, TRIPP launched its award-winning wellness application, TRIPP, in VR. The application offers immersive mindfulness experiences and, to date, has delivered nearly 6 million wellness sessions. TRIPP continues to work closely with neuroscience and psychiatry advisors through PsyAssist to design and evaluate their experiences and with a host of researchers who are studying its potential uses.

A recent clinical trial suggested that TRIPP might positively influence well-being and mood in cancer patients, and ongoing projects are assessing whether TRIPP can help people in recovery from substance use disorders or anxiety and pain control, among other initiatives.

“With some of the early data coming in, it seems very promising that tools like TRIPP might have a positive impact,” Reeves says, “but we are still only at the beginning of what may be possible with VR.”

Amazon Science spoke with Reeves about the motivation for TRIPP, its roots in science, and the implications for what it can achieve with VR.

  1. Q. 

    Why take meditation virtual?

    A. 

    It’s actually a super native case for VR, because the immersive quality allows you to unplug. You can’t look at your phone by nature of the immersion. I was blown away by how I felt moving in and out of VR — the feeling of respite.

    A lot of the early VR experiences simulated environments that made you terrified, like walking a plank or standing at the edge of a cliff. And it occurred to me: if we could scare people so easily, could we trigger other emotional changes that are beneficial?

    Our approach is to use immersion to drive a deeper connection to self-contemplative thoughts. You’re immersed in this psychologically safe container that is designed to capture your awareness, to allow you to be present and connect to self. With VR, it’s not just an audio file guiding you toward connecting with your breath. We can show you your breath, like star crystals coming in and out of your mouth.

    Some of the early offerings thought VR was really only for gaming. When we first got TRIPP on Oculus, they didn’t know where to put us because they didn’t have a relaxation genre then. We were pretty buried in the store. But we started to get a little bit of traction, and we soon had surprisingly regular usage over time. VR has this problem where you go in, you go, “Wow, that was amazing!” and then it's in your closet. You never pick it up again. When we were designing the product, we knew we had to build for repeat usage. So, we built it procedurally, and now we can update it from the server and add new content regularly.

  2. Q. 

    How is science leading the design and development of TRIPP?

    A. 

    I started by looking at the research investigating VR’s effect on the brain, largely by neuroscientists and behavioral therapists exploring mental health and medical use cases for VR. Most of them focused on simulation, like simulated exposure therapy. But I wondered if, instead of simulating something, could we stimulate responses? I took that question to the researchers working on VR and its effects on mental well-being. We started digging into the research and then, based on the research data, designed VR experiences intended to trigger states of wonder and awe. We tried them out on people and captured some physiological data like heart rate and EEG to see if the experiences were directionally achieving the effect we wanted.

    We stay very grounded in research-driven design choices. We’re a bit edgy. Rather than mimicking natural environments, the experiences are deliberately psychedelic. You find yourself inside an atom or floating in space. First, we tried things like a waterfall or a beach, but when we tested them, they didn’t feel good. I found some research describing how sensory dissonance in synthetic natural environments can create a stress response. Your brain goes, “Well, it looks like a beach, but I don’t smell the ocean. So what’s wrong with this environment?” We realized we had to create environments for which you have no mental model. So we said, “OK, let’s put you in a cosmic flotation tank, whatever that means, because no one knows what space smells like.”

    We’re also starting an enterprise program to support employee wellness and team-building with a hybrid workforce, but also with a focus on using the metaverse for driving ideation and innovation. Can we use these otherworldly environments to spark creativity?
    Nanea Reeves

    After we launched, we started collecting data on mood and emotional state in the live user sessions via self-reported surveys that are based on what they use in mental health research. We bookended our sessions with users, basically asking “How do you feel?” before and after each session. We did things like randomizing the order of the response selections to control against position bias. Now, we have data collected from close to 6 million sessions that we can slice and dice by the time of day and, for a percentage of our audience who opted in, age, gender, and location. It’s become a meaningful body of data that we can share with researchers once it has been de-identified. We also work with researchers who want to study TRIPP and its potential applications. It’s been fascinating to work with that community.

    One example is this group in Germany working with cancer patients undergoing surgery, looking at the effects of TRIPP sessions on their quality of life, well-being, and mood. This study was published in Nature’s Scientific Reports. Participation was good, and patients who used TRIPP had lower heart rates and breathing rates after their sessions. They had improved scores on their mood and emotion surveys after the sessions too. What the study shows us is that VR-based relaxation is a viable option and may be beneficial for cancer patients undergoing surgery. Of course, we don’t make any therapeutic claims until we have a tremendous amount of evidence to support those claims.

    You can find other published data and scientific reports examining TRIPP’s effects on adolescents and its use in palliative care. And we’re working with researchers who are looking at whether TRIPP could help people experiencing addiction and rehab, chemotherapy, severe mental illness, anxiety, and pain. Researchers are also using TRIPP to ease anxiety and help people prepare for ketamine-assisted therapy, so they get the most out of their treatment. I feel very motivated to see how we can help and participate in these research initiatives.

  3. Q. 

    How might TRIPP change how we use VR, beyond its medical applications?

    A. 

    Earlier this year, we acquired EvolVR, which holds live group meditations. Several hundred avatars attend the most popular conversations. People really open up. Skip Rizzo, PhD, a renowned researcher in the field and an advisor to TRIPP, did a pilot study and found that people suffering from PTSD were more open and honest with an avatar. We want to further investigate this as there’s something about the “digital veil” of VR where you don’t feel the judgment of being seen by other people. I think this is a wonderful use case for the metaverse.

    We’re also starting an enterprise program to support employee wellness and team-building with a hybrid workforce, but also with a focus on using the metaverse for driving ideation and innovation. Can we use these otherworldly environments to spark creativity?

    It’s also fascinating to think about the gig economy that could emerge from the metaverse — similar to what first emerged from mobile computing. For example, I met a woman at one of our live group meditation events in the metaverse who’s earning a living as one of the top world-builders in Altspace VR. She’s a mother of five who has never worked in tech before. She’s now a programmer, building these virtual worlds.

    We’re only beginning to explore the potential of VR. It’s like the early days of mobile. Initially, no one thought we’d want to play games or even text message on our cell phones. Now, for the past decade, we have been walking around with our heads down staring at these phone screens nonstop. What kind of innovation will happen in a future when XR glasses are ubiquitous and allow us to experience the world around us in an entirely new and adaptive way?

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We are seeking a Principal Applied Scientist to own the scientific vision across Agentic WorkSpaces. This is a foundational role spanning the full portfolio — Personal, Applications, and Core, and the agentic surfaces (WS4Builders and WorkSpaces for Agents). You will define how we measure, improve, and guarantee the performance of AI agents and human-AI teams. A core part of the role is defining the science agenda itself — identifying which problems are most worth solving and where the highest-leverage bets lie. Directions worth exploring might include Organizational Intelligence (turning institutional knowledge into agent-consumable skills), AI Agent Experience / AiAX (agent observability and autonomous remediation), and contextual, behavioral security that adapts enforcement in real time for human and agent sessions — but these are illustrative examples, not a fixed roadmap, and many other directions are possible. You will help define which ones we pursue. The problems you will solve do not have established industry patterns. You will set the direction for the science of how AI agents and people perceive, reason about, and act reliably within computing environments at enterprise scale. Key job responsibilities - Set the long-term scientific vision: Define what best-in-class agent performance, evaluation, and learning look like across Agentic WorkSpaces — for computer-using agents and human-AI teams alike. Identify the unsolved scientific problems, chart a multi-year research roadmap, and secure buy-in from VP-level leadership. - Solve highly ambiguous, novel problems: Independently frame and deliver solutions to foundational challenges in agent perception, reasoning, evaluation, reliability, and human-AI collaboration — problems where neither the approach nor the success criteria are pre-defined. - Own the evaluation and measurement foundation: Build the benchmarks, datasets, and metrics that quantify agent and team accuracy, cost, productivity, and safety across the portfolio and diverse enterprise workflows, and that gate what we ship. - Drive cross-organizational scientific alignment: Work across partner teams (AgentCore, Bedrock model teams, Identity, Security, the MCP ecosystem) and across the Applied AI Solutions product portfolio to shape how models and agent frameworks are applied, and ensure scientific decisions compose into a coherent system. - Deliver measurable business impact: Ensure research translates to customer outcomes: higher task accuracy, lower cost-per-action, faster time-to-production, measurable productivity for human-AI teams, and the trust that lets enterprises scale agent workflows. - Raise the scientific bar: Establish rigor in experimentation, evaluation, and reproducibility. Mentor and grow senior scientists and engineers. Set the standard for applied science quality across the organization. - Advance the state of the art: Contribute to the external technical community through publications, patents, and open-source contributions that position AWS as the leader in the science of secure agent-computer interaction and human-AI teamwork. About the team AWS Applied AI Solutions' (AAIS) vision is every business innovating with Amazon AI teammates. Our mission is to build delightful AI solutions that improve human capabilities and business outcomes. The Agentic WorkSpaces organization within AAIS envisions a world where people, teams, and AI collaborate securely from anywhere to create unprecedented value for every organization. We build lovable products that empower every business to unlock the full potential of human-AI teamwork, driving smarter decisions, greater creativity, more value, and faster innovation with confidence. Amazon Agentic WorkSpaces (AAWS) is building the world's most lovable, secure, and trusted always-on workspace where AI agents and humans work as partners behind enterprise-grade security. Our portfolio spans persistent desktops (Personal), application streaming (Applications), and Core, and is evolving into the governed operating environment for the hybrid workforce: humans get AI-native desktops for their role, and agents get governed desktops scoped to their task, with administrators managing both as one. This surface includes WS4Builders (an AI-native environment for builders) and WorkSpaces for Agents (W4A) — enabling AI agents to work the way humans do, with access to real applications, real interfaces, and real computing environments. Enterprises want to use AI agents for critical business workloads that touch legacy desktop applications and mainframes, yet 75% of organizations run legacy applications that lack modern APIs, and 90% of corporate data remains locked in systems never designed for agents. Agentic WorkSpaces solves this: it gives enterprises a secure, governed environment where agents and humans operate both legacy and modern applications directly, just as an employee would, without costly migrations.
US, WA, Seattle
We are seeking a Senior Manager, Applied Science to build and lead the science organization across Agentic WorkSpaces. This is a foundational leadership role spanning the full portfolio — Personal, Applications, and Core, and the agentic surfaces (WS4Builders and WorkSpaces for Agents). You will hire, grow, and lead a team of applied scientists who define how we measure and improve the performance of AI agents and human-AI teams. A core part of the role is defining the science agenda itself — identifying which problems are most worth solving and where the highest-leverage bets lie. Directions worth exploring might include Organizational Intelligence (turning institutional knowledge into agent-consumable skills), AI Agent Experience / AiAX (agent observability and autonomous remediation), and contextual, behavioral security that adapts enforcement in real time for human and agent sessions — but these are illustrative examples, not a fixed roadmap, and many other directions are possible. You and your team will define which ones we pursue. The problems your team will solve do not have established industry patterns. You will set the scientific direction and build the team that determines how AI agents and people perceive, reason about, and act reliably within computing environments at enterprise scale. What You Will Do Build and lead the applied science team. Hire, develop, and retain a high-caliber team of applied scientists spanning the Agentic WorkSpaces portfolio. Set the bar for scientific talent, create the growth paths, and build the culture that makes AAWS a destination for the best agent and human-AI researchers. Own the science strategy across the portfolio. Direct the research agenda for how we measure and improve agents and human-AI teams: the benchmarks, task suites, and metrics (accuracy, cost-per-task, task completion, productivity) that turn subjective "it works" judgments into rigorous, reproducible measurement that gates what we ship. Define and drive high-leverage research directions. Work with your team to identify the problems most worth solving and shape the science agenda. Directions worth exploring might include how agents combine deterministic tool use (MCP) with visual reasoning from computer use; Organizational Intelligence and workflow learning (learning from expert recordings, voice annotations, and SOPs); and AI Agent Experience / AiAX (detecting when agents are stuck or degrading productivity and autonomously remediating) — these are illustrative starting points, and your team will weigh them against many other possibilities. Translate science into shipped product. Partner with engineering, product, and program leaders to move models, evaluation, and learning systems from prototype into a decade-old production service operating at massive scale, without compromising the reliability that customers depend on. Represent science in leadership and to customers. Be the scientific voice in org-level planning and roadmap decisions across AAWS, and engage directly with enterprise customers on how agent performance, safety, and human-AI productivity are measured and earned. Key job responsibilities Build and lead the applied science team. Hire, develop, and retain a high-caliber team of applied scientists spanning the Agentic WorkSpaces portfolio. Set the bar for scientific talent, create the growth paths, and build the culture that makes AAWS a destination for the best agent and human-AI researchers. Own the science strategy across the portfolio. Direct the research agenda for how we measure and improve agents and human-AI teams: the benchmarks, task suites, and metrics (accuracy, cost-per-task, task completion, productivity) that turn subjective "it works" judgments into rigorous, reproducible measurement that gates what we ship. Define and drive high-leverage research directions. Work with your team to identify the problems most worth solving and shape the science agenda. Directions worth exploring might include how agents combine deterministic tool use (MCP) with visual reasoning from computer use; Organizational Intelligence and workflow learning (learning from expert recordings, voice annotations, and SOPs); and AI Agent Experience / AiAX (detecting when agents are stuck or degrading productivity and autonomously remediating) — these are illustrative starting points, and your team will weigh them against many other possibilities. Translate science into shipped product. Partner with engineering, product, and program leaders to move models, evaluation, and learning systems from prototype into a decade-old production service operating at massive scale, without compromising the reliability that customers depend on. Represent science in leadership and to customers. Be the scientific voice in org-level planning and roadmap decisions across AAWS, and engage directly with enterprise customers on how agent performance, safety, and human-AI productivity are measured and earned. Set the long-term scientific vision and team strategy: Define what best-in-class agent performance, evaluation, and learning look like across Agentic WorkSpaces — for computer-using agents and human-AI teams alike. Chart a multi-year research roadmap, and build the team and plan to deliver it. Secure buy-in from VP-level leadership. Hire and grow scientific talent: Own recruiting, calibration, development, and retention for the science team. Mentor scientists toward senior and principal scope, and raise the scientific bar across the organization. Direct research on highly ambiguous, novel problems: Guide the team through foundational challenges in agent perception, reasoning, evaluation, reliability, and human-AI collaboration — problems where neither the approach nor the success criteria are pre-defined. Drive cross-organizational alignment: Work across partner teams (AgentCore, Bedrock model teams, Identity, Security, the MCP ecosystem) and across the Applied AI Solutions product portfolio, with product and engineering leadership, to ensure scientific decisions compose into a coherent product. Deliver measurable business impact: Ensure your team's research translates to customer outcomes: higher task accuracy, lower cost-per-action, faster time-to-production, measurable productivity for human-AI teams, and the trust that lets enterprises scale agent workflows. Establish scientific rigor and operational excellence: Set the standard for experimentation, evaluation, and reproducibility, and the mechanisms that keep the science organization productive and accountable. Advance the state of the art: Enable and champion contributions to the external technical community through publications, patents, and open-source work that position AWS as the leader in the science of secure agent-computer interaction and human-AI teamwork. About the team AWS Applied AI Solutions' (AAIS) vision is every business innovating with Amazon AI teammates. Our mission is to build delightful AI solutions that improve human capabilities and business outcomes. The Agentic WorkSpaces organization within AAIS envisions a world where people, teams, and AI collaborate securely from anywhere to create unprecedented value for every organization. We build lovable products that empower every business to unlock the full potential of human-AI teamwork, driving smarter decisions, greater creativity, more value, and faster innovation with confidence. Amazon Agentic WorkSpaces (AAWS) is building the world's most lovable, secure, and trusted always-on workspace where AI agents and humans work as partners behind enterprise-grade security. Our portfolio spans persistent desktops (Personal), application streaming (Applications), and Core, and is evolving into the governed operating environment for the hybrid workforce: humans get AI-native desktops for their role, and agents get governed desktops scoped to their task, with administrators managing both as one. This surface includes WS4Builders (an AI-native environment for builders) and WorkSpaces for Agents (W4A) — enabling AI agents to work the way humans do, with access to real applications, real interfaces, and real computing environments. Enterprises want to use AI agents for critical business workloads that touch legacy desktop applications and mainframes, yet 75% of organizations run legacy applications that lack modern APIs, and 90% of corporate data remains locked in systems never designed for agents. Agentic WorkSpaces solves this: it gives enterprises a secure, governed environment where agents and humans operate both legacy and modern applications directly, just as an employee would, without costly migrations.
IN, HR, Gurugram
Work on ML teams building large-scale forecasting and optimization systems that power Amazon’s global transportation network and directly impact customer experience and cost. As an Applied Scientist II, you will set scientific direction, mentor applied scientists, and partner with engineering and product leaders to deliver production-grade ML solutions at massive scale. Key job responsibilities 1. Lead and grow a high-performing team of Applied Scientists, providing technical guidance, mentorship, and career development. 2. Define and own the scientific vision and roadmap for ML solutions powering large-scale transportation planning and execution. 3. Guide model and system design across a range of techniques, including tree-based models, deep learning (LSTMs, transformers), LLMs, and reinforcement learning. 4. Ensure models are production-ready, scalable, and robust through close partnership with stakeholders. Partner with Product, Operations, and Engineering leaders to enable proactive decision-making and corrective actions. 5. Own end-to-end business metrics, directly influencing customer experience, cost optimization, and network reliability. 6. Help contribute to the broader ML community through publications, conference submissions, and internal knowledge sharing. A day in the life Your day includes reviewing model performance and business metrics, guiding technical design and experimentation, mentoring scientists, and driving roadmap execution. You’ll balance near-term delivery with long-term innovation while ensuring solutions are robust, interpretable, and scalable. Ultimately, your work helps improve delivery reliability, reduce costs, and enhance the customer experience at massive scale.